Acting COO.  James has 20 years industry experience, including 12 years with AstraZeneca.  While there, he held a number of commercial, R&D and Bus Dev roles, including VP Global Marketing for CV/GI Therapy Area, Global Product VP for Crestor and most recently VP Evaluation for the CV/Metabolism Therapy Area.  Prior to this he was a member of the Pharmaceutical/Medical Products practice at McKinsey & Co.  He has an MB BCh and a Ph.D. in Cell Physiology from Oxford University where he was a Rhodes Scholar.