Blocking of Ca2+-channels β3 subunit reverses diabetes On the web-site of Karolinska Institutet, there is a recent press release regarding new findings, published in the scientific journal Cell Reports; “Researchers at Karolinska Institutet have discovered that one of the building blocks in the calcium channels in the pancreatic beta cells play an important role in …
As has been published on the Karolinska Institutet’s website, Per-Olof Berggren, Professor of Experimental Endocrinology and Research Group Leader of the group Signal Transduction at the Department of Molecular Medicine and Surgery has been elected member of the Korean Academy of Science and Technology, KAST. Read more: Press release in English: Per-Olof Berggren elected member of the Korean Academy …
The body’s “glucostat” identified On the web-site of Karolinska Institutet, there is a recent post regarding a new findings, published in the scientific journal Cell Metabolism; “It is the pancreatic islets that have the overall responsibility for maintaining normal blood glucose levels in our bodies, according to a new study by researchers at Karolinska Institutet …
Pancreatic islet blood flow dynamics in primates On the web-site of Karolinska Institutet, there is recent post regarding a new publication in the scientific journal Cell Reports. “Researchers have established a unique method enabling them to study the function of insulin-producing cells under conditions that are similar to those in humans. This can pave the way …
Per-Olof Berggren has been elected to The National Academy of Medicine The National Academy of Medicine announced today the election of 70 U.S. members and 9 international members during its annual meeting. Election to the Academy is considered one of the highest honors in the fields of health and medicine and recognizes individuals who have …
New non-invasive method for studying the development of insulin-producing cells On the web-site of Karolinska Institutet, there is recent post regarding a new publication: “Researchers at Karolinska Institutet and Nanyang Technological University in Singapore have produced a unique method for monitoring the development of insulin-producing cells, which play a key part in regulating blood glucose …
Insulin-secreting cells report on insulin resistance On the web-site of Karolinska Institutet, there is a recent post (see “Research news”) regarding a new publication: “Diabetes researchers at Karolinska Institutet have developed a novel technique that makes it possible to monitor insulin resistance in a non-invasive manner over time in mice. The new method, presented in …
Liraglutide compromises pancreatic beta cell function in a humanized mouse model On the web-site of Karolinska Institutet, there is a recent post regarding a new publication of high impact: “Long-term use of liraglutide, a substance that helps to lower blood sugar levels in patients with type 2 diabetes, can have a deteriorating effect on insulin-producing …
Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets. Insulin secretion plays a central role in glucose homeostasis and diabetes. However, all aspects of the macroscopic secretory pattern at the cellular level are not totally clear. The results from a study presented in the December 2015 issue of Diabetologia, reveal how …
New insights into the architecture of the islet of Langerhans: a focused cross-species assessment. Many studies on human islet cells rely on the legacy of rodent-based investigations. Since islet physiology and pathology may differ between rodents and humans, the current knowledge of interspecies islet cell cytoarchitecture and its potential impact on islet function is reviewed …