Regulation of glucose homeostasis using radiogenetics and magnetogenetics in mice Endogenous expression of tailored nanoparticles in cells followed by application of low-frequency radio waves or a magnetic field can be used to noninvasively modulate gene expression. This approach successfully induces insulin transgene expression in diabetic mice. Read more: Regulation of glucose homeostasis using radiogenetics and …
The results from new findings about the molecular mechanisms behind the age-dependent deterioration in β-cell function have been published in Advances in Biological Regulation (formerly Advances in Enzyme Regulation); a journal reporting cutting edge scientific progress on regulation at the molecular level. Defects in pancreatic β-cell function and survival are key components in type 2 diabetes. …
Young capillary vessels rejuvenate aged pancreatic islets. A recent study published in the journal PNAS shows that young capillary vessels rejuvenate aged pancreatic islets. This finding challenges the common view that pancreatic beta-cells become inefficient with age. The reduction of insulin production within the cells may instead be affected by systemic aging factors. Read more: Press release …
Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents. In a study, presented in Nature Communications, we investigated the role of primary cilia in islet function and glucose homeostasis. This is possibly the first study to address the role of primary cilia in glucose handling, insulin signalling and T2DM …
Science Daily reports on InSight Technology on the 29th of January, 2014. The website Science Daily reports on how the InSight Technology has been applied to the studying of the inflammatory process that occurs in the pancreas during type 1 diabetes. Unlike other non-invasive techniques such as PET and MRI, the InSight technology enables in …
Images of the researchers in Professor Per-Olof Berggren’s group were presented an Biomedical Picture of the Day (BPoD) on the 31st of December 2013. BPoD stands for Biomedical Picture of the Day. The website is managed by the MRC Clinical Sciences Centre. It aims to engage everyone in the wonders of biomedicine. Images are provided by the …
InSight Technology was featured in the Research Report section of Wall Street Journal on the 23rd of December 2013 Wall Street Journal reports on the possibility to study molecular and cellular processes in the pancreatic islets by using InSight Technology. The report is published on the 23rd of December 2013 in the Research Report section. …
A possibility to study the islets of Langerhans in a mouse eye is reported by NyTeknik on the 2nd of December 2013. Researchers in P-O Berggren’s group have come with a solution to study diabetes progress and effectiveness of a treatment program and exercising. If one places insulin-producing islets of Langerhans into a mouse eye, …
InSight Technology was recently reported on by Swedish news channel TV4. See more: Ny forskning ger hopp för diabetiker. TV4 2013/11/28
Swedish daily newspaper DN reports on the possibility to study islets of Langerhans in the eye on the 19th of November 2013. DN presents InSight Technology and its possibilities in an article published on the 19th of November 2013. Islets of Langerhans are placed into a mouse eye. They reflect the processes happening in the islets …