Swedish daily newspaper DN reports on the possibility to study islets of Langerhans in the eye on the 19th of November 2013. DN presents InSight Technology and its possibilities in an article published on the 19th of November 2013. Islets of Langerhans are placed into a mouse eye. They reflect the processes happening in the islets …
Swedish news channel SVT Vetenskap reports on the InSight Technology on the 19th of November 2013. The islets of Langerhans placed in the mouse eye behave in the same way as the islets in the pancreas. It opens for a possibility to study the progress of diabetes by looking into a patient’s eye. One can …
Swedish Crown Princess Victoria visited Rolf Luft Research Center at KI and Professor P-O Berggren’s group on the 14th of November, the International Diabetes Day. During the visit, the Crown Princess got introduced to diabetes and its complications, as well as to new findings, the research group’s projects and InSight Technology. Read more: Report published …
On the 26th of September the European Research Council (ERC) announced 284 senior research leaders, who will be awarded funding after the last Advanced Grant competition. The competition was carried out under the EU’s Seventh Research Framework Programme (FP7). Professor P-O Berggren is one of the 8 Swedish researchers to receive the Advanced ERC Grant. The …
The exact cause of either type 1 or type 2 diabetes still remains unknown. Inflammation of the insulin-producing islets of Langerhans seems to be one of the common denominators during the early stage of both diseases. InSight Technology is a promising analytical tool for studying the inflammation processes. The review is published in Diabetes, Obesity …
Signal transduction between the diabetogenic blood factor apolipoprotein CIII (apoCIII) and insulin-producing beta cells is now clarified. ApoCIII acts upon the calcium channels through kinases PKA and Src, involving a receptor SR-BI and an integrin beta1. The results are published in Cellular and Molecular Life Sciences on the 15th of August 2013. Calcium is very …
Advantages of and protocols for using InSight Technology as an imaging platform are presented in the March 2013 issue of the Journal of Visualized Experiments. Intravital, performed in the living organism, imaging has become an important tool in life sciences. A number of different technologies have emerged over the years and have been adapted to …
Researchers in Professor P-O Berggren’s group proposed utilizing InSight Technology to answer questions of islet development during infancy and puberty and to describe a ”point-of-no-return” for islet development programming. The commentary is published in Molecular Metabolism in January 2013. Genes and obesity are two major factors that contribute to the development of type 2 diabetes …
Professor Per-Olof Berggren has received 4 major distinctions during 2012: Alex Hirsch from Karolinska Institutet, Wallenberg Scholars, The Novo Nordisk Foundation Advanced Grant and Kroc Lecture at Boston University Medical Center. Professor Berggren’s distinctions are for the following achievements: Axel Hirsch Prize from Karolinska Institutet. The prize is for scientific achievements, which are potentially of major significance to the treatment of …
Blood glucose levels are controlled by the autonomous nervous system. Parasympathetic axons directly influence islet function, leading to higher insulin release and lower levels of blood glucose. The results are published in December 2012 in PNAS. The autonomous nervous system responsible for the unconscious regulation consists of parasympathetic and sympathetic parts, managing the calm and …