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Home » News » Publication » Pancreatic NMDA receptors as possible drug targets

Pancreatic NMDA receptors as possible drug targets

Pancreatic NMDA receptors as possible drug targets.

In contrast to NMDA receptors in the nervous system, the role of NMDA receptors in pancreatic islets and the insulin-secreting beta cells is less known. Data presented in the April issue of Nature Medicine bring new understanding of the cell processes involved in type 2 diabetes mellitus and highlight the possibility that antagonists of NMDARs may provide a useful adjunct treatment for diabetes.

Read more:    Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment. Jan Marquard, Silke Otter, Alena Welters, Alin Stirban, Annelie Fischer, Jan Eglinger, Diran Herebian, Olaf Kletke, Maša Skelin Klemen, Andraž Stožer, Stephan Wnendt, Lorenzo Piemonti, Martin Köhler, Jorge Ferrer, Bernard Thorens, Freimut Schliess, Marjan Slak Rupnik, Tim Heise, Per-Olof Berggren, Nikolaj Klöcker, Thomas Meissner, Ertan Mayatepek, Daniel Eberhard, Martin Kragl and  Eckhard Lammert. Nature Medicine, 21, 363-372 (2015), doi:10.1038/nm.3822

September 2, 2020 Catharina Rahm

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