A promising way to delay onset of type 1 diabetes is to reduce the concentration of apolipoprotein CIII (apoCIII) in blood. This discovery is presented in a newly published article in PNAS from June 2011. It took twice as long for the rats that have undergone therapy reducing apoCIII to develop …
New success of the InSight* technology is now presented in an article in PNAS from July 18th, 2011. Using this unique technology in a mouse model, reactions of the immune system to implanted islets of Langerhans were for the first time observed in a living organism. Following an allogeneic transplantation of beta …
Endothelial cells lining surfaces of donor islets promote a faster initial blood vessel formation after transplantation. The results are published in Diabetes in October 2011. Patients with type 1 diabetes lack insulin, as the majority of the pancreatic beta cells producing this vital hormone have been destroyed. Transplanting donor islets of Langerhans, built up primarily …
Insulin shots for patients with type 1 diabetes can become history. A novel site to transplant donor islet of Langerhans may give a chance to cure patients’ own failing insulin production. When transplanted into the anterior chamber of the eye of a diabetic monkey, pancreatic islets survive and produce insulin, reducing …