Young capillary vessels rejuvenate aged pancreatic islets. A recent study published in the journal PNAS shows that young capillary vessels rejuvenate aged pancreatic islets. This finding challenges the common view that pancreatic beta-cells become inefficient with age. The reduction of insulin production within the cells may instead be affected by systemic aging factors. Read more: Press release …
Ciliary dysfunction impairs beta-cell insulin secretion and promotes development of type 2 diabetes in rodents. In a study, presented in Nature Communications, we investigated the role of primary cilia in islet function and glucose homeostasis. This is possibly the first study to address the role of primary cilia in glucose handling, insulin signalling and T2DM …